Ascorbic acid, iron overload, and desferrioxamine.
نویسندگان
چکیده
منابع مشابه
Effects of iron overload on ascorbic acid metabolism.
Studies of the ascorbic acid status in two subjects with idiopathic haemochromatosis and in 12 with transfusional siderosis showed that all had decreased levels of white cell ascorbic acid. The urinary excretion of ascorbic acid was also diminished in those subjects in whom such measurements were made. The administration of ascorbic acid was followed by only a small rise in the urinary ascorbic...
متن کاملLow Dose Intravenous Ascorbic Acid for Erythropoietin- Hyporesponsive Anemia in Hemodialysis Patients with Iron Overload
Department of Nephrology, Chang Gung Memorial Hospital, Chiayi, Taiwan Chang-Gung Memorial hospital, Department of Nephrology at Linko* Received: March, 2002 Revised: April, 2002 Accepted: May, 2002 Reprint requests address: Chun-Liang Lin, MD, Department of Nephrology Chang Gung Memorial Hospital, Chiayi (613) 6 West, Chia-Pu Road, Pu-tzu City, Chiayi, Taiwan Tel: (05) 3621000 ext. 2762 Fax: (...
متن کاملDesferrioxamine chelatable body iron.
Further experience with the differential ferrioxamine test (Fielding, 1965) for the measurement of body-iron chelation has led to modifications which include (1) an improved standard for the estimation of ferrioxamine, (2) simplified preparation of the test dose, (3) restriction of fluid during the test and (4) simplified methods of calculation. The principle of the test remains the same: an in...
متن کاملAscorbic acid status in iron-deficiency anaemia.
Leucocyte ascorbic acid concentration declines with age. Patients with iron-deficiency anaemia have higher concentrations than normal while those with iron overload have a reduced concentration. It is suggested that these phenomena may be a result of reduced ascorbate catabolism in iron-deficiency anaemia and they provide support for the suggestion that the amount of iron in the tissues may be ...
متن کاملEffect of ascorbic acid deficiency on serum ferritin concentration in patients with beta-thalassaemia major and iron overload.
The incidence of ascorbic acid (AA) deficiency and its effect on serum ferritin concentration relative to body iron stores was studied in 61 unchelated patients with beta-thalassaemia major. Thirty-nine (64%) of patients had subnormal leucocyte ascorbate concentrations without clinical evidence of scurvy. The lowest leucocyte ascorbate concentrations tended to occur in the most transfused patie...
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ژورنال
عنوان ژورنال: BMJ
سال: 1982
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.285.6337.296